BDBM577562 2-[[3-[(3R,4R)-4-Methoxytetrahydrofuran-3-yl]oxy-1-methyl-pyrazol-4-yl]amino]-7-[(3R,4R)-4-methyltetrahydrofuran-3-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile::WO2022263472, Example 12

SMILES CO[C@H]1COC[C@@H]1ON(c1cnn(C)c1)c1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1

InChI Key InChIKey=MMFIITGVKCNEED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577562   

LigandPNGBDBM577562(WO2022263472, Example 12 | 2-[[3-[(3R,4R)-4-Methox...)
Affinity DataIC50: 6nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472

LigandPNGBDBM577562(WO2022263472, Example 12 | 2-[[3-[(3R,4R)-4-Methox...)
Affinity DataIC50: 8nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472