BDBM577575 2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-yl)amino)-7-((3S,4R)-4-methyltetrahydrofuran-3-yl)-7H-pyrrolo[2,3-d]pyrimidine-6-carbonitrile::2-((1-Methyl-3-(oxetan-3-yloxy)-1 H-pyrazol-4-yl)amino)-7-((3S,4S)-4-methyltetrahydrofuran-3-yl)-7H-pyrrolo[2,3-d]pyrimidine-6-carbonitrile::WO2022263472, Example 44

SMILES C[C@@H]1COC[C@H]1n1c(cc2cnc(Nc3cn(C)nc3OC3COC3)nc12)C#N

InChI Key InChIKey=SUPJRVMWGQZUOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577575   

LigandPNGBDBM577575(WO2022263472, Example 44 | 2-((1-Methyl-3-(oxetan-...)
Affinity DataIC50: 1nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472

LigandPNGBDBM577575(WO2022263472, Example 44 | 2-((1-Methyl-3-(oxetan-...)
Affinity DataIC50: 196nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472