BDBM577587 2-((1-((S)-1-Cyanoethyl)-3-isopropoxy-1 H-pyrazol-4-yl)amino)-7-((3R,4R)-4-methoxytetrahydrofuran-3-yl)-7H-pyrrolo[2,3-d]pyhmidine-6-carbonithle::WO2022263472, Example 56

SMILES CO[C@H]1COC[C@H]1n1c(cc2cnc(Nc3cn(nc3OC(C)C)[C@H](C)C#N)nc12)C#N

InChI Key InChIKey=XCPQHDAJUNOSMI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577587   

LigandPNGBDBM577587(WO2022263472, Example 56 | 2-((1-((S)-1-Cyanoethyl...)
Affinity DataIC50: 4nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472

LigandPNGBDBM577587(WO2022263472, Example 56 | 2-((1-((S)-1-Cyanoethyl...)
Affinity DataIC50: 7nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472