BDBM578154 US11478467, Compound (-)-52

SMILES COc1ccc(CCc2ccccc2OC[C@H](CN(C)C)OC(=O)CCC(O)=O)cc1

InChI Key InChIKey=DBZZSKZFWFZAHO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 578154   

Target5-hydroxytryptamine receptor 2A(Human)
Exciva

US Patent
LigandPNGBDBM578154(US11478467, Compound (-)-52)
Affinity DataKi:  6.31nMAssay Description:Evaluation of the affinity of compounds for the human 5-HT2A receptor in transfected HEK-293 cells determined in a radioligand binding assay. Cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Exciva

US Patent
LigandPNGBDBM578154(US11478467, Compound (-)-52)
Affinity DataIC50: 11nMAssay Description:Evaluation of the affinity of compounds for the human 5-HT2A receptor in transfected HEK-293 cells determined in a radioligand binding assay. Cell me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Exciva

US Patent
LigandPNGBDBM578154(US11478467, Compound (-)-52)
Affinity DataIC50: 1.30E+3nMAssay Description:Dextromethorphan O-demethylase activity was determined in human liver microsomes. Sarpogrelate (1.0E-8 M to 3.0E-5 M) or M−1 (concentration: 3....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent