BDBM579143 US11479553, Compound 1.033

SMILES CCc1cccc(CC)c1-n1nc2c(CN(C(=O)C(C)(C)C(F)(F)F)C2(C)C)c1-c1ccc(F)c2[nH]ccc12

InChI Key InChIKey=YEWWNMQKAQXUEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579143   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM579143(US11479553, Compound 1.033)
Affinity DataIC50: 27.5nMAssay Description:To evaluate small organic molecules that prevent the C5a receptor from binding ligand, an assay was employed that detected radioactive ligand (i.e, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent