BDBM580005 US11485736, Compound TABLE 4.34::US11485736, Compound Table 2.14

SMILES CC(C)c1ccccc1-c1ncc2ncn(Cc3ccc(cc3)-c3nc(cn3C)C(F)(F)F)c2n1

InChI Key InChIKey=STFQWLOAUNAWMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580005   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Ksq Therapeutics

US Patent
LigandPNGBDBM580005(US11485736, Compound Table 2.14 | US11485736, Comp...)
Affinity DataIC50: 55nMAssay Description:Deubiquitinase activity was measured using ubiquitin-rhodamine 110 as a substrate. Cleavage of the amide bond between rhodamine and the c-terminal gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Ksq Therapeutics

US Patent
LigandPNGBDBM580005(US11485736, Compound Table 2.14 | US11485736, Comp...)
Affinity DataIC50: 55nMAssay Description:Deubiquitinase activity was measured using ubiquitin-rhodamine 110 as a substrate. Cleavage of the amide bond between rhodamine and the c-terminal gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent