BDBM580111 US11485736, Compound TABLE 4.29

SMILES COc1ncnc(C2CC2)c1-c1ncc2nc(C)n(Cc3ccc(cc3)-n3nc(cc3C)C(F)(F)F)c2n1

InChI Key InChIKey=KPJVZGDUCSHZQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580111   

TargetUbiquitin carboxyl-terminal hydrolase 1(Human)
Ksq Therapeutics

US Patent
LigandPNGBDBM580111(US11485736, Compound TABLE 4.29)
Affinity DataIC50: 55nMAssay Description:Deubiquitinase activity was measured using ubiquitin-rhodamine 110 as a substrate. Cleavage of the amide bond between rhodamine and the c-terminal gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent