BDBM580206 (3S,4S)-8-(8-((6-amino-2,3-dichloropyridin-4-yl)thio)imidazo[1,2-c]pyrimidin-5-yl)-3-methyl-2-oxa-8-azaspiro[4.5]decan-4-amine::US11498930, Compound 1.1.16

SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3cc(N)nc(Cl)c3Cl)c3nccn23)[C@@H]1N

InChI Key InChIKey=IUWYPCSCEYVSCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580206   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Blueray Therapeutics (Shanghai)

US Patent
LigandPNGBDBM580206(US11498930, Compound 1.1.16 | (3S,4S)-8-(8-((6-ami...)
Affinity DataIC50: 100nMAssay Description:Compound powders were dissolved in DMSO to prepare mother liquor.During the experiment, the stock solutions of the compounds were subjected to 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
Go to US Patent