BDBM580343 (R)-8-(8-((3-chloro-2-methylpyridin-4-yl)thio)-[1,2,4]triazolo[4,3-c]pyrimidin-5-yl)-8-azaspiro[4.5]decan-1-amine::US11498930, Compound 1.2.39

SMILES Cc1nccc(Sc2cnc(N3CCC4(CCC[C@H]4N)CC3)n3cnnc23)c1Cl

InChI Key InChIKey=FORDWTGKWXAPCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580343   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Blueray Therapeutics (Shanghai)

US Patent
LigandPNGBDBM580343(US11498930, Compound 1.2.39 | (R)-8-(8-((3-chloro-...)
Affinity DataIC50: 100nMAssay Description:Compound powders were dissolved in DMSO to prepare mother liquor.During the experiment, the stock solutions of the compounds were subjected to 3-fold...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent