BDBM580404 N-[[6-(1-benzyl-3,5-dimethyl- pyrazole-4-carbonyl)-6- azaspiro[2.5]octan-2- yl]methyl]furo[2,3-c]pyridine-2- carboxamide::US11485745, Example 295

SMILES Cc1nn(Cc2ccccc2)c(C)c1C(=O)N1CCC2(CC2CNC(=O)c2cc3ccncc3o2)CC1

InChI Key InChIKey=VSBKDIKZVRWAOH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580404   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580404(US11485745, Example 295 | N-[[6-(1-benzyl-3,5-dime...)
Affinity DataIC50: 14.5nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
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Date in BDB:
1/6/2023
Entry Details
US Patent