BDBM580419 US11491148, Compound C26::US11491148, Compound C29R*

SMILES C[C@H]2[C@@H](C(=O)Nc1cc(F)c(F)c(F)c1)CCN2C(=O)C(=O)N[C@H](CC(F)(F)F)c3nn[nH]c3Cl

InChI Key InChIKey=LWVAPMAIGKGFAG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 580419   

TargetCapsid protein(HBV)
Janssen Sciences Ireland

US Patent
LigandPNGBDBM580419(US11491148, Compound C26 | US11491148, Compound C2...)
Affinity DataEC50:  14nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetCapsid protein(HBV)
Janssen Sciences Ireland

US Patent
LigandPNGBDBM580419(US11491148, Compound C26 | US11491148, Compound C2...)
Affinity DataEC50:  176nMAssay Description:The anti HBV activity was measured using the HepG2.117 cell line, a stable, inducible HBV producing cell line, which replicates HBV in the absence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent