BDBM580454 N-[[6-[4-[(4-methylpiperazin-1- yl)methyl]benzoyl]-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US11485745, Example 346

SMILES CN1CCN(Cc2ccc(cc2)C(=O)N2CCC3(CC3CNC(=O)N3Cc4ccncc4C3)CC2)CC1

InChI Key InChIKey=LFIOQTMGZARJHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580454   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580454(US11485745, Example 346 | N-[[6-[4-[(4-methylpiper...)
Affinity DataIC50: 10.3nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent