BDBM580469 N-[[6-[4-(4-methylpiperazin-1- yl)benzoyl]-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US11485745, Example 362

SMILES CN1CCN(CC1)c1ccc(cc1)C(=O)N1CCC2(CC2CNC(=O)N2Cc3ccncc3C2)CC1

InChI Key InChIKey=HVSBSRDSVBDKHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580469   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580469(US11485745, Example 362 | N-[[6-[4-(4-methylpipera...)
Affinity DataIC50: 9.69nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent