BDBM580507 N-[[6-[4-(1-methyl-4- piperidyl)benzoyl]-6- azaspiro[2.5]octan-2-yl]methyl]- 1,3-dihydropyrrolo[3,4- c]pyridine-2-carboxamide::US11485745, Example 405

SMILES CN1CCC(CC1)c1ccc(CN2CCC3(CC3CNC(=O)N3Cc4ccncc4C3)CC2)cc1

InChI Key InChIKey=WYTRVMMXEKLVKO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 580507   

TargetNicotinamide phosphoribosyltransferase(Human)
Valo Health

US Patent
LigandPNGBDBM580507(US11485745, Example 405 | N-[[6-[4-(1-methyl-4- pi...)
Affinity DataIC50: 6.37nMAssay Description:The NAMPT enzymatic reactions were carried out in Buffer A (50 mM Hepes pH 17.5, 50 mM NaCl, 5 mM MgCl2, and 1 mM THP) in 96-well V-bottom plates. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent