BDBM581216 5-(3-(2-(pyridin-3- yl)ethynyl)phenoxy)-1H-1,2,3- triazole-4-carboxylic acid::US11504367, Example 312

SMILES OC(=O)c1nn[nH]c1Oc1cccc(c1)C#Cc1cccnc1

InChI Key InChIKey=UXVTWBLSRAYKPJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581216   

Target2-Hydroxyacid oxidase 1(Human)
Oxalurx

US Patent
LigandPNGBDBM581216(US11504367, Example 312 | 5-(3-(2-(pyridin-3- yl)...)
Affinity DataIC50: 3nMAssay Description:The in-vitro glycolate oxidase assay was performed using recombinant full-length human hydroxyacid oxidase 1 (HAO1), the equivalents of hGOX. The enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent