BDBM581350 US11505526, Compound IV-6

SMILES O=C(C1CCCN(Cc2ccccc2)C1)c1ccncc1

InChI Key InChIKey=HFQMNUFWOZYARV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 581350   

TargetCytochrome P450 1A2(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 3.50E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 5.00E+3nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Artax Biopharma

US Patent
LigandPNGBDBM581350(US11505526, Compound IV-6)
Affinity DataIC50: 1.25E+4nMAssay Description:The effect of compounds IV-6, IV-7, and V-4 on Cytochromes P450 (CYP) inhibition was evaluated. For each isozyme, microsomes-buffer-substrate mixture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
Go to US Patent