BDBM581819 US11512080, Compound I-139

SMILES O=C1CCC(Sc2cc(ccn2)-c2nn[nH]n2)C(=O)N1

InChI Key InChIKey=XJLFTIQMZBSNPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581819   

TargetProtein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM581819(US11512080, Compound I-139)
Affinity DataIC50: 5.50E+3nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
US Patent