BDBM581839 WO2022208262, Example 1::WO2022208262, Example 35

SMILES CC(C)[C@H](NC(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COc1ccc(F)cc1F)C2(C)C

InChI Key InChIKey=JKEMJOJIXMMUNI-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 581839   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581839(WO2022208262, Example 1 | WO2022208262, Example 35)
Affinity DataKi:  2.02nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581839(WO2022208262, Example 1 | WO2022208262, Example 35)
Affinity DataKi:  2.76nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581839(WO2022208262, Example 1 | WO2022208262, Example 35)
Affinity DataEC50:  27nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581839(WO2022208262, Example 1 | WO2022208262, Example 35)
Affinity DataEC50:  94nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262