BDBM581862 WO2022208262, Example 38

SMILES CC(C)(C)[C@H](NS(=O)(=O)C(F)(F)F)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)N[C@@H](C[C@@H]1CC(O)NC1=O)C(=O)COc1ccc(F)cc1F)C2(C)C

InChI Key InChIKey=RHSHREOWUFBIOC-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581862   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581862(WO2022208262, Example 38)
Affinity DataKi:  4.12nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262

TargetReplicase polyprotein 1ab(2019-nCoV)
Pfizer

WIPO
LigandPNGBDBM581862(WO2022208262, Example 38)
Affinity DataEC50:  1.39E+3nMAssay Description: The ability of compounds to prevent SARS-CoV-2 coronavirus-induced cell death or cytopathic effect can be assessed via cell viability, using an assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022208262