BDBM581890 WO2022224223, Example 20a::WO2022224223, Example 20b

SMILES Fc1cccc2cncc(-n3c(=O)n(CCC#N)c4ccc(cc4c3=O)C(F)(F)F)c12

InChI Key InChIKey=VGUWXIPGMSQCSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581890   

TargetReplicase polyprotein 1ab(2019-nCoV)
Novartis

WIPO
LigandPNGBDBM581890(WO2022224223, Example 20a | WO2022224223, Example ...)
Affinity DataIC50: 20nMAssay Description: Assay buffer preparation: 50 mM HEPES pH 7.3, 150 mM NaCl, 1 mM EDTA, 0.01% pluronic f-127(Catalog # 59005, Biotium) was prepared using UltraPure Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022224223

TargetReplicase polyprotein 1ab(2019-nCoV)
Novartis

WIPO
LigandPNGBDBM581890(WO2022224223, Example 20a | WO2022224223, Example ...)
Affinity DataIC50: 1.00E+3nMAssay Description: Assay buffer preparation: 50 mM HEPES pH 7.3, 150 mM NaCl, 1 mM EDTA, 0.01% pluronic f-127(Catalog # 59005, Biotium) was prepared using UltraPure Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/31/2023
Entry Details
WIPO WO2022224223