BDBM582883 US11548892, Compound 22

SMILES COC(=O)N[C@@H](CC\C=C\C(=O)N(C)C)C(=O)Nc1cccn(Cc2nc3c(CC(C)C)c(F)c(F)cc3n2C(=O)OC(C)(C)C)c1=O

InChI Key InChIKey=BNVRBKFIYGSRBO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582883   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Sitari Pharma

US Patent

LigandBDBM582883(US11548892, Compound 22)Copy SMILESCopy InChI

Affinity DataIC50: 500nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/6/2023
Entry Details
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