BDBM585680 US11530213, Example 1

SMILES OC[C@H](O)COc1ncc(Cl)c2n(c(CO)cc(=O)c12)-c1c(Cl)cccc1Cl

InChI Key InChIKey=DDDSGZFENQKDDY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 585680   

LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 104nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human Cav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human KCNQ1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585680(US11530213, Example 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant hERG in the presence of dofetilide by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed