BDBM587508 US11535596, Compound CNS22

SMILES COc1ccc2C=CC3CCCCC3(CN(C)CC=C)c2c1

InChI Key InChIKey=OQPJQNGJTWFIBM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 587508   

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataKi:  20.5nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataIC50: 29.1nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataKi:  3.81E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587508(US11535596, Compound CNS22)
Affinity DataIC50: 5.25E+3nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent