BDBM587515 US11535596, Compound CNS1-D2

SMILES CN1CCC23CCCCC2C1Cc1ccc(OCC(F)F)cc31

InChI Key

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 587515   

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataKi:  40.6nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataIC50: 57.8nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandPNGBDBM587515(US11535596, Compound CNS1-D2)
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent