BDBM587550 N-hydroxy-4-((3-(4- (methylamino)phenethyl)- 2,4-dioxo-3,4- dihydroquinazolin- 1(2H)- yl)methyl)benzamide::US11535598, Compound 29

SMILES CNc1ccc(CCn2c(=O)n(Cc3ccc(cc3)C(=O)NO)c3ccccc3c2=O)cc1

InChI Key InChIKey=LYRGQYWDWZHBQJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 587550   

TargetHistone deacetylase 6(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587550(US11535598, Compound 29 | N-hydroxy-4-((3-(4- (met...)
Affinity DataIC50: 25nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587550(US11535598, Compound 29 | N-hydroxy-4-((3-(4- (met...)
Affinity DataIC50: 1.42E+3nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587550(US11535598, Compound 29 | N-hydroxy-4-((3-(4- (met...)
Affinity DataIC50: 3.80E+3nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587550(US11535598, Compound 29 | N-hydroxy-4-((3-(4- (met...)
Affinity DataIC50: 4.38E+3nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent