BDBM587554 N-hydroxy-4-((3-(4- morpholinophenethyl)- 2,4-dioxo-3,4- dihydroquinazolin- 1(2H)- yl)methyl)benzamide::US11535598, Compound 30

SMILES ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3ccc(cc3)N3CCOCC3)c2=O)cc1

InChI Key InChIKey=WMWNLURBMXMZLD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 587554   

TargetHistone deacetylase 6(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587554(US11535598, Compound 30 | N-hydroxy-4-((3-(4- morp...)
Affinity DataIC50: 14nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587554(US11535598, Compound 30 | N-hydroxy-4-((3-(4- morp...)
Affinity DataIC50: 979nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587554(US11535598, Compound 30 | N-hydroxy-4-((3-(4- morp...)
Affinity DataIC50: 9.79E+3nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetHistone deacetylase 11(Human)
Annji Pharmaceutical

US Patent
LigandPNGBDBM587554(US11535598, Compound 30 | N-hydroxy-4-((3-(4- morp...)
Affinity DataIC50: 2.28E+4nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent