BDBM588058 US11541023, Compound 6

SMILES CC(C)c1ccc(C(=O)Nc2ccc(CN)cc2)c(O)c1

InChI Key InChIKey=LERYNNIOTWZURB-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 588058   

TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataIC50: 1.56E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetKallikrein-1(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataIC50: 8.44E+3nMAssay Description:Table 4: The molecules were tested in order to evaluate their possible inhibitory effect on the enzymatic activity of KLK1. The % inhibitions were de...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetPlasminogen(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataIC50: 4.78E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetPlasminogen(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataKi:  670nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetKallikrein-6(Human)
Sarbonne Universite

US Patent
LigandPNGBDBM588058(US11541023, Compound 6)
Affinity DataKi:  1.75E+3nMAssay Description:In a typical test, 100 μl of reaction medium contains the buffer, 1 μl of recombinant enzyme, 1 μl of substrate (Boc-QAR-AMC) and 1 &#...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent