BDBM588186 (S)-(4-(3-(2-Aminoethyl)-5- fluorobenzoyl)piperazin-1-yl)(5- (4-fluorophenyl)-6-(pyrrolidin-3- yloxy)pyridin-3-yl)methanone hydrochloride::US11542254, Example 4

SMILES [NH3+]CCc1cc(F)cc(c1)C(=O)N1CCN(CC1)C(=O)c1cnc(O[C@H]2CC[NH2+]C2)c(c1)-c1ccc(F)cc1

InChI Key InChIKey=VIUQIWNIPLKQHD-UHFFFAOYSA-P

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588186   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588186((S)-(4-(3-(2-Aminoethyl)-5- fluorobenzoyl)piperazi...)
Affinity DataKi: >5.00E+5nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent