BDBM588189 (4-(3-Fluoro-5-(((R)-pyrrolidin-3- yl)oxy)benzoyl)piperazin-1-yl) (4'-fluoro-6-(((S)-pyrrolidin-3-yl) oxy)-[1,1'-biphenyl]-3-yl) methanone hydrochloride::US11542254, Example 7

SMILES Fc1ccc(cc1)-c1cc(ccc1O[C@H]1CC[NH2+]C1)C(=O)N1CCN(CC1)C(=O)c1cc(F)cc(O[C@@H]2CC[NH2+]C2)c1

InChI Key InChIKey=IFNJIMKJHDWVCU-UHFFFAOYSA-P

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588189   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588189((4-(3-Fluoro-5-(((R)-pyrrolidin-3- yl)oxy)benzoyl)...)
Affinity DataKi:  3.50E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent