BDBM588197 (S)-(4-(3-(4,4- Dimethylcyclohexyl)-4-(pyrrolidin- 3-yloxy)benzoyl)piperazin-1-yl) (3-fluoro-5-(piperazin-1-yl)phenyl) methanone hydrochloride::US11542254, Example 15

SMILES Fc1cc(cc(c1)C(=O)N1CCN(CC1)C(=O)c1ccc(O[C@H]2CC[NH2+]C2)c(c1)C1CCC(F)(F)CC1)N1CC[NH2+]CC1

InChI Key InChIKey=ZGIGDPVEUDPANG-UHFFFAOYSA-P

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588197   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588197((S)-(4-(3-(4,4- Dimethylcyclohexyl)-4-(pyrrolidin-...)
Affinity DataKi:  4.50E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent