BDBM588208 (S)-1-(3-(4-(3-Cyclohexyl-4- (pyrrolidin-3-yloxy)benzoyl) piperazine-1-carbonyl)-5- fluorophenyl)piperazin-2-one hydrochloride::US11542254, Example 75

SMILES Fc1cc(cc(c1)C(=O)N1CCN(CC1)C(=O)c1ccc(O[C@H]2CC[NH2+]C2)c(c1)C1CCCCC1)N1CC[NH2+]CC1=O

InChI Key InChIKey=DBYZNLNDOZWZIH-UHFFFAOYSA-P

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588208   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588208((S)-1-(3-(4-(3-Cyclohexyl-4- (pyrrolidin-3-yloxy)b...)
Affinity DataKi:  3.90E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent