BDBM5884 CHEMBL185387::N-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]benzenesulfonamide::isoindolinone analog 16

SMILES O=C1NCc2c1cccc2-c1ccc(NS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=ZRCRWIFHCHDKSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5884   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5884(CHEMBL185387 | N-[4-(1-oxo-2,3-dihydro-1H-isoindol...)
Affinity DataIC50: 5.00E+4nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed