BDBM58857 (E)-3-(3-methylphenyl)-1-(5-nitro-2-furanyl)-2-propen-1-one::(E)-3-(3-methylphenyl)-1-(5-nitrofuran-2-yl)prop-2-en-1-one::(E)-3-(m-tolyl)-1-(5-nitro-2-furyl)prop-2-en-1-one::MLS001240993::SMR000841201::cid_6054676

SMILES Cc1cccc(\C=C\C(=O)c2ccc(o2)[N+]([O-])=O)c1

InChI Key InChIKey=AWMRZIZNWUQMIM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 58857   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58857(SMR000841201 | MLS001240993 | (E)-3-(3-methylpheny...)
Affinity DataEC50:  3.43E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58857(SMR000841201 | MLS001240993 | (E)-3-(3-methylpheny...)
Affinity DataEC50:  9.69E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58857(SMR000841201 | MLS001240993 | (E)-3-(3-methylpheny...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay