BDBM588890 US11548890, Compound I-486

SMILES CC(C)(O)[C@H]1CN(CCO1)c1ccc(Nc2cnc(c3CNC(=O)c23)-c2cnc3cnccn23)nc1

InChI Key InChIKey=GKQJWABSDYKBRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588890   

LigandPNGBDBM588890(US11548890, Compound I-486)
Affinity DataIC50: 100nMAssay Description:HPK1 biochemical enzyme assay: HPK1 enzyme inhibition was measured using a microfluidic mobility shift assay. Reactions were performed in a 384-well ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent