BDBM589026 1-(10-((3- chloro-4- (pyridin-2- ylmethoxy) phenyl)amino)- 2,3-dihydro-4H- [1,4]oxazino[2,3- f]quinazolin- 4-yl)prop-2-en- 1-one::US11548900, Example 4

SMILES Clc1cc(Nc2ncnc3ccc4N(CCOc4c23)C(=O)C=C)ccc1OCc1ccccn1

InChI Key InChIKey=KEVPYOVOSUZBKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 589026   

TargetEpidermal growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589026(US11548900, Example 4 | 1-(10-((3- chloro-4- (pyri...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589026(US11548900, Example 4 | 1-(10-((3- chloro-4- (pyri...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent