BDBM589046 1-(10-((4- (benzylthio) phenyl)amino)- 2,3-dihydro-4H- [1,4]oxazino[2,3- f]quinazolin- 4-yl)prop-2-en- 1-one::US11548900, Example 24

SMILES C=CC(=O)N1CCOc2c1ccc1ncnc(Nc3ccc(SCc4ccccc4)cc3)c21

InChI Key InChIKey=AFXYJVOLPDLFJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589046   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589046(US11548900, Example 24 | 1-(10-((4- (benzylthio) p...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent