BDBM589047 1-(10-((4-((3- fluorobenzyl) oxy)-3- (trifluoromethyl) phenyl)amino)- 2,3-dihydro- 4H- [1,4]oxazino[2,3- f]quinazolin- 4-yl)prop-2-en- 1-one::US11548900, Example 25

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc5N(CCOc5c34)C(=O)C=C)cc2C(F)(F)F)c1

InChI Key InChIKey=PAUKGMLRJOCFDI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589047   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589047(US11548900, Example 25 | 1-(10-((4-((3- fluorobenz...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
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Date in BDB:
3/6/2023
Entry Details
US Patent