BDBM589055 1-(10-(4- phenoxyphenoxy)- 2,3-dihydro-4H- [1,4]oxazino[2,3- f]quinazolin- 4-yl)prop-2-en- 1-one::US11548900, Example 33

SMILES C=CC(=O)N1CCOc2c1ccc1ncnc(Oc3ccc(Oc4ccccc4)cc3)c21

InChI Key InChIKey=MTDIVUHLZRLNNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 589055   

TargetEpidermal growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589055(US11548900, Example 33 | 1-(10-(4- phenoxyphenoxy)...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589055(US11548900, Example 33 | 1-(10-(4- phenoxyphenoxy)...)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent