BDBM589066 US11548900, Example 43

SMILES CN(C)C\C=C\C(=O)N1CCOc2c1ccc1ncnc(Nc3ccc(Oc4cccc(c4)C(F)(F)F)cc3)c21

InChI Key InChIKey=KHQXWUMYLBQLEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 589066   

TargetEpidermal growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589066(US11548900, Example 43)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM589066(US11548900, Example 43)
Affinity DataIC50: 50nMAssay Description:The assay for the inhibition of EGFR and HER2 kinase activity by small molecular compounds was carried out using the method as follows:1) Dilution of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details
US Patent