BDBM5894 3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]-1-[4-(trifluoromethyl)phenyl]urea::CHEMBL364626::isoindolinone analog 4f

SMILES FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)-c2cccc3C(=O)NCc23)cc1

InChI Key InChIKey=YVMPCLMMNBMFFZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5894   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5894(3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]-1...)
Affinity DataIC50: 161nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed