BDBM589737 US11559538, Example 1::US11559538, Example 221::US11559538, Example 32

SMILES COc1ccc(cc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=LAXVRAQRHWZVHW-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589737   

LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 2.21nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 2.43E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 47.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 9.35nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 3.16nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 284nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 14.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 2.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 13nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 2.25E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 64nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589737(US11559538, Example 1 | US11559538, Example 32 | U...)
Affinity DataIC50: 8.47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent