BDBM5903 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]urea::CHEMBL184170::isoindolinone analog 4o

SMILES Fc1ccc(cc1NC(=O)Nc1ccc(cc1)-c1cccc2C(=O)NCc12)C(F)(F)F

InChI Key InChIKey=IXBGEUWAAIXICM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5903   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5903(1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-(1-oxo...)
Affinity DataIC50: 23nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed