BDBM5909 1-(3-methylphenyl)-3-[4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)-2-(trifluoromethyl)phenyl]urea::CHEMBL183174::isoindolinone analog 10f

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2C(F)(F)F)-c2cccc3C(=O)NCc23)c1

InChI Key InChIKey=UCOGAOPSFPFQQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5909   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5909(CHEMBL183174 | 1-(3-methylphenyl)-3-[4-(1-oxo-2,3-...)
Affinity DataIC50: 34nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed