BDBM5920 3-{4-[7-(2-methoxyethoxy)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]phenyl}-1-(3-methylphenyl)urea::CHEMBL365448::isoindolinone analog 27

SMILES COCCOc1ccc(c2CNC(=O)c12)-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=GULMNVJVAFUDLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 5920   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM5920(CHEMBL365448 | 3-{4-[7-(2-methoxyethoxy)-1-oxo-2,3...)
Affinity DataIC50: 126nMpH: 7.4 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase and biotinylated poly-Glu-Ala-Tyr substrate. HTRF is based on the proximity of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2005
Entry Details Article
PubMed