BDBM59230 Pyrazolopyrimidone analog, RGB-285960

SMILES CC(C)c1nn(-c2c(Cl)cccc2Cl)c2nc(Cc3ccc(OCCN4CCOCC4)cc3)[nH]c(=O)c12

InChI Key InChIKey=OUYYPCVVBYQBJK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 59230   

LigandPNGBDBM59230(Pyrazolopyrimidone analog, RGB-285960)
Affinity DataIC50: 310nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59230(Pyrazolopyrimidone analog, RGB-285960)
Affinity DataIC50: 9nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59230(Pyrazolopyrimidone analog, RGB-285960)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59230(Pyrazolopyrimidone analog, RGB-285960)
Affinity DataIC50: 64nMAssay Description:Inhibition of HCT116 cell proliferation after 72hr of incubation with compounds was determined by SRB Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed