BDBM59235 PEGylated derivative, RGB-286276

SMILES COCCOCCOCCOc1ccc(Cc2nc3n(nc(C(C)C)c3c(=O)[nH]2)-c2c(Cl)cccc2Cl)cc1

InChI Key InChIKey=QUTOYIJHSFPXBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 59235   

LigandPNGBDBM59235(PEGylated derivative, RGB-286276)
Affinity DataIC50: 84nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59235(PEGylated derivative, RGB-286276)
Affinity DataIC50: 22nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59235(PEGylated derivative, RGB-286276)
Affinity DataIC50: 890nMAssay Description:In vitro kinase activity of PEGylated pyrazolopyrimidone CDK inhibitor or a 5 PEG-amine was coupled to ReactiGel agarose beads (Pierce, No. 20259).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed
LigandPNGBDBM59235(PEGylated derivative, RGB-286276)
Affinity DataIC50: 34nMAssay Description:Inhibition of HCT116 cell proliferation with compounds using calcein AM Assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2011
Entry Details Article
PubMed