BDBM592419 US11572368, Compound 56

SMILES Nc1ccc(cc1NC(=O)C1CCCCO1)-c1cccs1

InChI Key InChIKey=QUBMXRRMOBLEGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 592419   

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM592419(US11572368, Compound 56)
Affinity DataIC50: 50nMAssay Description:HDAC2: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC2-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM592419(US11572368, Compound 56)
Affinity DataIC50: 50nMAssay Description:HDAC1: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. Trypsin Coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM592419(US11572368, Compound 56)
Affinity DataIC50: 3.05E+3nMAssay Description:HDAC3: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC3-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent