BDBM592434 US11572368, Compound 115

SMILES Cc1ccc(s1)-c1ccc(N)c(NC(=O)N2CCCC2)c1

InChI Key InChIKey=BLGPUEACEVLTFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 592434   

TargetHistone deacetylase 2(Human)
The General Hospital

US Patent
LigandPNGBDBM592434(US11572368, Compound 115)
Affinity DataIC50: 50nMAssay Description:HDAC2: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC2-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
The General Hospital

US Patent
LigandPNGBDBM592434(US11572368, Compound 115)
Affinity DataIC50: 50nMAssay Description:HDAC1: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. Trypsin Coupled...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetHistone deacetylase 3(Human)
The General Hospital

US Patent
LigandPNGBDBM592434(US11572368, Compound 115)
Affinity DataIC50: 1.76E+4nMAssay Description:HDAC3: The following trypsin-coupled protocol and Caliper protocol described Herein was used to assay the compounds of the invention. HDAC3-Kinetic I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent