BDBM592990 US11578054, Example 1013

SMILES Cc1c(OCCCN2CC[C@@H](O)C2)cccc1-c1cccc2C(CCc12)Oc1cc(OCc2cncc(c2)C#N)c(CO)cc1Cl

InChI Key InChIKey=RKXLFHNDNMJPSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 592990   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM592990(US11578054, Example 1013)
Affinity DataIC50: 18.1nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2023
Entry Details
US Patent