BDBM593524 N-({5-[5-(difluoromethyl)-1,3,4-oxadiazol-2- yl]-1,3-thiazol-2-yl}methyl)-N-{5-[(1S)-1- fluoroethyl]pyridin-3-yl}methanesulfonamide::US11578066, Compound I-216::US20230381148, Compound I-216::US20240269137, Compound I-216
SMILES C[C@H](F)c1cncc(c1)N(Cc1ncc(s1)-c1nnc(o1)C(F)F)S(C)(=O)=O
InChI Key InChIKey=COOCVHGZVGGWAX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 593524
Affinity DataIC50: 11.9nMAssay Description:Table 13: The compounds disclosed herein, in particular those of Formula (I), were synthesized according to methods disclosed in PCT/US2020/066439, p...More data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:The compounds disclosed herein were tested for potency against HDAC6 and selectivity against HDAC1 in a biochemical assay. A biochemical assay was ad...More data for this Ligand-Target Pair
Affinity DataIC50: 11.9nMAssay Description:A biochemical assay was adopted using a luminescent HDAC-Glo I/II assay (Promega) and measured the relative activity of HDAC6 and HDAC1 recombinant p...More data for this Ligand-Target Pair